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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 629303Generated: October 31, 2026

Hydrochloric Acid → HCID 178427324, compound

https://huagongshe.com/reaction/629303

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
ReactantWaterHCID 962—
Reactant4-[5-(2,4-difluorophenoxy)-1-(tetrahydro-2H-pyran-2-yl)-1H-1,2,3-benzotriazol-6-yl]-6-methyl-1-[(4-methylphenyl)sulfonyl]-1,6-dihydro-7H-pyrrolo[2,3-c]pyridin-7-oneHCID 118093658—
SolventMethanolHCID 887—
ProductHCID 178427324HCID 178427324—

Reaction Conditions

Temperature20 °C

Reaction Steps

A solution of 4-[5-(2,4-difluorophenoxy)-1-(tetrahydro-2H-pyran-2-yl)-1H-1,2,3-benzotriazol-6-yl]-6-methyl-1-[(4-methylphenyl)sulfonyl]-1,6-dihydro-7H-pyrrolo[2,3-c]pyridin-7-one (0.077 g, 0.12 mmol) in methanol (0.34 mL) was treated with 6.0 M hydrogen chloride in water (0.102 mL, 0.610 mmol) and stirred at 20° C. for 22 h. The reaction mixture was concentrated to give a crude residue that was used immediately without further purification.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09315501B2
Source datasetuspto-grants-2016_04
ORD IDord-c22f635e1dff4ee089cc4c05fa27d4f4
Source noteuspto-grants-2016_04