HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 629303Generated: October 31, 2026
Hydrochloric Acid → HCID 178427324, compound
https://huagongshe.com/reaction/629303
Participants
| Role | Name | HCID | Charge |
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| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | Water | HCID 962 | — |
| Reactant | 4-[5-(2,4-difluorophenoxy)-1-(tetrahydro-2H-pyran-2-yl)-1H-1,2,3-benzotriazol-6-yl]-6-methyl-1-[(4-methylphenyl)sulfonyl]-1,6-dihydro-7H-pyrrolo[2,3-c]pyridin-7-one | HCID 118093658 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | HCID 178427324 | HCID 178427324 | — |
Reaction Steps
A solution of 4-[5-(2,4-difluorophenoxy)-1-(tetrahydro-2H-pyran-2-yl)-1H-1,2,3-benzotriazol-6-yl]-6-methyl-1-[(4-methylphenyl)sulfonyl]-1,6-dihydro-7H-pyrrolo[2,3-c]pyridin-7-one (0.077 g, 0.12 mmol) in methanol (0.34 mL) was treated with 6.0 M hydrogen chloride in water (0.102 mL, 0.610 mmol) and stirred at 20° C. for 22 h. The reaction mixture was concentrated to give a crude residue that was used immediately without further purification.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US09315501B2 |
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| Source dataset | uspto-grants-2016_04 |
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| ORD ID | ord-c22f635e1dff4ee089cc4c05fa27d4f4 |
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| Source note | uspto-grants-2016_04 |
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