HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 59419852, compound → 3-[4-(6-Sec-butylsulfanyl-pyridin-2-ylmethoxy)-3,5-difluoro-phenyl]-2-methyl-propionic acid ethyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 59419852 | HCID 59419852 | — |
| Reactant | HCID 90117937 | HCID 90117937 | — |
| Product | 3-[4-(6-Sec-butylsulfanyl-pyridin-2-ylmethoxy)-3,5-difluoro-phenyl]-2-methyl-propionic acid ethyl ester | HCID 90118044 | 96% |
Reaction Steps
2-sec-Butylsulfanyl-6-chloromethyl-pyridine (28 mg, 0.13 mmol) in Step C of Preparation Example 5 and 3-(3,5-difluoro-4-hydroxy-phenyl)-2-methyl-propionic acid ethyl ester (30 mg, 0.13 mmol) in Step B of Preparation Example 34 were used to react in the same manner as in Step A of Example 1 to obtain the title compound (50 mg, 96%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09447044B2 |
| Source dataset | uspto-grants-2016_09 |
| ORD ID | ord-6541f957eb964f589f0a641155eedddf |
| Source note | uspto-grants-2016_09 |