N,N-Dimethylethylenediamine → HCID 71542099, compound

HRID 629523Notes

Reaction equation

HRID 629523 reaction equation
[C:1]12([C:11]3[CH:21]=[CH:20][C:14]([O:15][CH2:16][C:17](O)=[O:18])=[C:13]([CH3:22])[CH:12]=3)[CH2:10][CH:5]3[CH2:6][CH:7]([CH2:9][CH:3]([CH2:4]3)[CH2:2]1)[CH2:8]2.[CH3:23][N:24]([CH3:28])[CH2:25][CH2:26][NH2:27]>>[C:1]12([C:11]3[CH:21]=[CH:20][C:14]([O:15][CH2:16][C:17]([NH:27][CH2:26][CH2:25][N:24]([CH3:28])[CH3:23])=[O:18])=[C:13]([CH3:22])[CH:12]=3)[CH2:10][CH:5]3[CH2:4][CH:3]([CH2:9][CH:7]([CH2:6]3)[CH2:8]1)[CH2:2]2

Participants

3

Reactant 2

HCID 66053N,N-DimethylethylenediamineHCID 86729431HCID 86729431, compound

Product 1

HCID 71542099HCID 71542099, compoundYield 90%

Procedure

The title compound was prepared from 2-(4-(adamantan-1-yl)-2-methylphenoxy)acetic acid (0.2 g, 0.66 mmol), prepared from the step 4 of the example 5, and N,N-dimethylethane-1,2-diamine (0.058 g, 0.66 mmol) according to the example 1, which was given 2-(4-(adamantan-1-yl)-2-methylphenoxy)-N-(2-(dimethylamino)ethyl)acetamide as a white solid (0.22 g, 89.4% yield).

Sources & evidence

ORD record
ord-28b0e01970894219bb0543e49da55263
Source dataset
uspto-grants-2016_04
Patent number
US09315507B2

Reaction notes

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