反应详情

To a solution of EXAMPLE 403B (2.76 g) in tetrahydrofuran (125 mL) in a stainless steel pressure bottle was added nickel catalyst (2.76 g). The mixture was stirred for 1 hour under hydrogen at 30 psi and ambient temperature. The mixture was filtered though a nylon membrane to remove the catalyst, and concentrated to give the product.

1. filtrationThe mixture was filtered though a nylon membrane
2. customto remove the catalyst
3. concentrationconcentrated
4. customto give the product