Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 62967Generated: October 25, 2026

HCID 58566718, compound → 3-[3-Chloro-4-(2-propylsulfanyl-pyridin-3-ylmethoxy)-phenyl]-2-methyl-propionic acid

https://huagongshe.com/reaction/62967

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 58566718HCID 58566718—
Reactant3-Chloromethyl-2-propylsulfanyl-pyridineHCID 90118282—
Product3-[3-Chloro-4-(2-propylsulfanyl-pyridin-3-ylmethoxy)-phenyl]-2-methyl-propionic acidHCID 7422288875%

Reaction Steps

3-Chloromethyl-2-propylsulfanyl-pyridine (32 mg, 0.15 mmol) obtained in Step C of Preparation Example 14 and 3-(3-chloro-4-hydroxy-phenyl)-2-methyl-propionic acid ethyl ester (42 mg, 0.17 mmol) obtained in Step B of Preparation Example 46 were used to react sequentially in the same manner as in Steps A and B of Example 1 to obtain the title compound (40 mg, 75%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09447044B2
Source datasetuspto-grants-2016_09
ORD IDord-8091803f94b64cb284f242bda7d2f21a
Source noteuspto-grants-2016_09