3,4-Dihydroisoquinoline → HCID 117601998, compound

HRID 629811Notes

Reaction equation

HRID 629811 reaction equation
[CH3:1][O:2][CH:3]1[CH2:8][CH2:7][N:6]([C:9]2[CH:18]=[CH:17][CH:16]=[C:15]3[C:10]=2[CH2:11][CH2:12][NH:13][CH2:14]3)[CH2:5][CH2:4]1.C1C2C(=CC=CC=2)CCN=1>>[CH3:1][O:2][CH:3]1[CH2:8][CH2:7][N:6]([C:9]2[CH:18]=[CH:17][CH:16]=[C:15]3[C:10]=2[CH2:11][CH2:12][N:13]=[CH:14]3)[CH2:5][CH2:4]1

Participants

3

Reactant 2

HCID 767053,4-DihydroisoquinolineHCID 81215199HCID 81215199, compound

Product 1

HCID 117601998HCID 117601998, compoundYield 100%

Procedure

Intermediate 3B was oxidized as described for Intermediate 2 to afford 6.32 g (100%) of Intermediate 3 as a yellow viscous oil. MS (ESI) m/z: 245.2 (M+H)+.

Sources & evidence

ORD record
ord-e41a599aca414923af3bfa0909532ac6
Source dataset
uspto-grants-2016_04
Patent number
US09315519B2

Reaction notes

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