HRID629860
反应详情
EQUATION
反应方程式
REACTANTS
反应物
PRODUCTS
生成物
AUXILIARIES
试剂、催化剂与溶剂
CONDITIONS
反应条件
- 温度
- 50 °C
PROCEDURE
实验过程
1-(2,2-Dimethylpropyl)-5-[2-(4-methoxyphenyl)-2-azabicyclo[2.2.2]oct-5-en-5-yl]-3-methyl-1,3-dihydro-2H-imidazo[4,5-b]pyridin-2-one (2-4, 339 mg, 0.78 mmol, 1.0 equiv) was added to CH3CN (7 mL) and water (7 mL) To this suspension was added aqueous H2SO4 (0.78 mL, 0.78 mmol, 1.0 equiv, 1.0 M) followed by periodic acid in one portion (179 mg, 0.78 mmol, 1.0 equiv). The reaction contents were heated to 50° C. for 18 h. Following this duration,
WORKUP
后处理
- customThe reaction contents