HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
HCID 22558806, Verbindung → 3-[3-Fluoro-4-(2-propylsulfanyl-pyridin-3-ylmethoxy)-phenyl]-propionic acid
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | HCID 22558806 | HCID 22558806 | — |
| Edukt | 3-Chloromethyl-2-propylsulfanyl-pyridine | HCID 90118282 | — |
| Produkt | 3-[3-Fluoro-4-(2-propylsulfanyl-pyridin-3-ylmethoxy)-phenyl]-propionic acid | HCID 90118312 | 73% |
Reaktionsschritte
3-Chloromethyl-2-propylsulfanyl-pyridine (0.030 g, 0.15 mmol) obtained in Step C of Preparation Example 14 and 3-(3-fluoro-4-hydroxy-phenyl)-propionic acid methyl ester (0.031 g, 0.15 mmol) obtained in Step C of Preparation Example 6 were used to react sequentially in the same manner as in Steps A and B of Example 1 to obtain the title compound (0.038 g, 73%).
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US09447044B2 |
| Quelldatensatz | uspto-grants-2016_09 |
| ORD ID | ord-db553c0fd7c24bf1a09305fe26841a30 |
| Quellennotiz | uspto-grants-2016_09 |