HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethyl 3-(3-fluoro-4-hydroxyphenyl)propionate → HCID 74221851, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethyl 3-(3-fluoro-4-hydroxyphenyl)propionate | HCID 3023769 | — |
| Reactant | 2-Chloromethyl-6-isopropylsulfanyl-pyridine | HCID 90118141 | — |
| Product | HCID 74221851 | HCID 74221851 | 83.8% |
Reaction Steps
2-Chloromethyl-6-isopropylsulfanyl-pyridine (0.028 g, 0.14 mmol) obtained in Step C of Preparation Example 16 and 3-(3-fluoro-4-hydroxy-phenyl)-propionic acid ethyl ester (0.030 g, 0.14 mmol) obtained in Step C of Preparation Example 6 were used to react sequentially in the same manner as in Steps A and B of Example 1 to obtain the title compound (0.041 g, 83%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09447044B2 |
| Source dataset | uspto-grants-2016_09 |
| ORD ID | ord-1d18889fcc214a79a39908c269ff52e9 |
| Source note | uspto-grants-2016_09 |