HuagongsheHuagongshe Chemistry Print Report · For research reference only
N-[4-({[tert-butyl(dimethyl)silyl]oxy}methyl)-2-chlorophenyl]acrylamide → HCID 178483940, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | N-[4-({[tert-butyl(dimethyl)silyl]oxy}methyl)-2-chlorophenyl]acrylamide | HCID 67145162 | — |
| Reactant | HCID 178484861 | HCID 178484861 | — |
| Reactant | HCID 178493273 | HCID 178493273 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 178483940 | HCID 178483940 | — |
Reaction Steps
Obtained as a beige solid (45%) starting from N-[4-({[tert-butyl(dimethyl)silyl]oxy}-methyl)-2-chlorophenyl]-acrylamide (intermediate 47; 0.56 g, 1.73 mmol) and trans-4-(methylamino)cyclohexyl hydroxy(di-2-thienyl)acetate (intermediate 5; 0.5 g, 1.42 mmol) in 14 ml dichloromethane and following the experimental procedure as described for intermediate 41.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09315463B2 |
| Source dataset | uspto-grants-2016_04 |
| ORD ID | ord-de4de64076c742c1ac2df0f17b050acc |
| Source note | uspto-grants-2016_04 |