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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 630544Generated: October 31, 2026

2-chloro-4-cyclopropylpyridine → HCID 118676831, compound

https://huagongshe.com/reaction/630544

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-chloro-4-cyclopropylpyridineHCID 45787914—
ReactantMethyl 1-(5-bromopyrimidin-2-yl)-3-(methylthio)-1H-indole-6-carboxylateHCID 118666039—
ProductHCID 118676831HCID 118676831—

Reaction Steps

Synthesized from methyl 1-(5-bromopyrimidin-2-yl)-3-(methylthio)-1H-indole-6-carboxylate (1.7 g, 4.49 mmol) and 2-chloro-4-cyclopropylpyridine (1.03 g, 6.73 mmol) in analogy to the procedures 141a) and b). White solid. Yield: 1.2 g (64% of theory)

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09315490B2
Source datasetuspto-grants-2016_04
ORD IDord-8ecb973843e444ca9e12cf92663a40a3
Source noteuspto-grants-2016_04