反应详情

After 5.0 g of 1-(9,9-di-n-butyl-7-nitrofluorene-2-yl)-ethanone (6) (13.7 mmol) was dispersed in 150 ml of ethanol and 1.04 g of hydroxylamine hydrochloride (15.1 mmol) and 1.24 g of sodium acetate (15.1 mmol) were added thereto, the reaction mixture was slowly heated and refluxed for 1 hour. The reaction mixture was cooled to room temperature and 100 ml of distilled water was added thereto. Then, a solid product obtained by stirring the reaction mixture for about 30 minutes was filtered and washed with distilled water several times, followed by drying, thereby obtaining 4.89 g of 1-(9,9-di-n-butyl-7-nitrofluorene-2-yl)-ethanone oxime (7) (93.9%) as a light yellow product.

1. temperaturethe reaction mixture was slowly heated
2. temperaturerefluxed for 1 hour
3. customThen, a solid product obtained
4. filtrationwas filtered
5. washwashed with distilled water several times
6. customby drying