反应详情

tert-Butyl N-[3-(4-methyl-2-pyridyl)propyl]carbamate (522 mg, 2.085 mmol) was dissolved in methanol (1 ml). A solution of HCl in methanol (4N, 41.7 mmol, 10.43 ml) was added and the mixture was stirred at room temperature for 2 hours. The mixture was concentrated under reduced pressure and triturated several times with diethyl ether. The residue was dried in vacuo to obtain a brown solid (409 mg, quantitative). MS(ESI) m/z=151.2 [M+1]+.

1. concentrationThe mixture was concentrated under reduced pressure
2. customtriturated several times with diethyl ether
3. customThe residue was dried in vacuo
4. customto obtain a brown solid (409 mg, quantitative)