Hydrochloric Acid → 7-(4-Methyl-2-pyridyl)-2,7-diazaspiro[4.5]decane dihydrochloride

Participants

Reaction Steps

The residue of step A was dissolved in a mixture of methanol and hydrochloric acid (4M in dioxane, 5 ml) and stirred at room temperature overnight. The mixture was concentrated under reduced pressure to yield 79 mg of a solid (quantitive) that was used directly in the next step.

Provenance & Evidence