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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 631968Generated: October 25, 2026

Methyl 2-amino-2-methylpropanoate → 2-{[6-Cyclopropylmethoxy-5-(tetrahydro-pyran-4-yl)-pyridine-2-carbonyl]-amino}-2-methyl-propionic acid methyl ester

https://huagongshe.com/reaction/631968

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethyl 2-amino-2-methylpropanoateHCID 4186341—
Reactant6-Cyclopropylmethoxy-5-(tetrahydro-pyran-4-yl)-pyridine-2-carboxylic acidHCID 71087401—
Product2-{[6-Cyclopropylmethoxy-5-(tetrahydro-pyran-4-yl)-pyridine-2-carbonyl]-amino}-2-methyl-propionic acid methyl esterHCID 71087340—

Reaction Steps

The title compound was synthesized in analogy to Example 1, using 6-cyclopropylmethoxy-5-(tetrahydro-pyran-4-yl)-pyridine-2-carboxylic acid and 2-methyl-alanine methyl ester as starting materials, MS (EI): m/e 377.2 [M+H]+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09321727B2
Source datasetuspto-grants-2016_04
ORD IDord-e6744c87ff4b45fd9504b78e4c351106
Source noteuspto-grants-2016_04