Piperidine → [5-Methyl-6-(piperidine-1-sulfonyl)-pyridin-2-yl]-piperidin-1-yl-methanone
Reaction equation
[CH3:1][C:2]1[CH:3]=[CH:4][C:5]([C:17]([OH:19])=O)=[N:6][C:7]=1[S:8]([N:11]1[CH2:16][CH2:15][CH2:14][CH2:13][CH2:12]1)(=[O:10])=[O:9].[NH:20]1[CH2:25][CH2:24][CH2:23][CH2:22][CH2:21]1>>[CH3:1][C:2]1[CH:3]=[CH:4][C:5]([C:17]([N:20]2[CH2:25][CH2:24][CH2:23][CH2:22][CH2:21]2)=[O:19])=[N:6][C:7]=1[S:8]([N:11]1[CH2:12][CH2:13][CH2:14][CH2:15][CH2:16]1)(=[O:9])=[O:10]Participants
3
Procedure
The title compound was synthesized in analogy to Example 1, using 5-methyl-6-(piperidine-1-sulfonyl)-pyridine-2-carboxylic acid and piperidine (CAN 110-89-4) as starting materials, MS (EI): 352.2 [M+H]+.
Sources & evidence
- ORD record
- ord-1fdbfc902b14450c9ab4f405d0229b91
- Source dataset
- uspto-grants-2016_04
- Patent number
- US09321727B2
Reaction notes
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