HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → 3-Amino-3-methyl-1-morpholinobutan-1-one hydrochloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | tert-Butyl 2-methyl-4-morpholino-4-oxobutan-2-ylcarbamate | HCID 71105557 | — |
| Solvent | Ethyl Acetate | HCID 8857 | — |
| Product | 3-Amino-3-methyl-1-morpholinobutan-1-one hydrochloride | HCID 71087648 | — |
Reaction Steps
tert-Butyl 2-methyl-4-morpholino-4-oxobutan-2-ylcarbamate (0.5 g, 1.7 mmol) was dissolved in a saturated solution of hydrogen chloride in ethyl acetate (20 mL). The mixture was stirred for 3 h. The solvent was removed by reduced pressure to give crude product (0.55 g).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09321727B2 |
| Source dataset | uspto-grants-2016_04 |
| ORD ID | ord-9ca036de6a294b7abad6f9e5120cb904 |
| Source note | uspto-grants-2016_04 |