HuagongsheHuagongshe Chemistry Print Report · For research reference only
(S)-alpha-(2-methylpropyl)-2-thiazolemethanamine → 6-Cyclopropylmethoxy-5-methyl-pyridine-2-carboxylic acid ((S)-3-methyl-1-thiazol-2-yl-butyl)-amide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (S)-alpha-(2-methylpropyl)-2-thiazolemethanamine | HCID 42078239 | — |
| Reactant | 6-Cyclopropylmethoxy-5-methyl-pyridine-2-carboxylic acid | HCID 71087599 | — |
| Product | 6-Cyclopropylmethoxy-5-methyl-pyridine-2-carboxylic acid ((S)-3-methyl-1-thiazol-2-yl-butyl)-amide | HCID 71105574 | — |
Reaction Steps
The title compound was synthesized in analogy to Example 1, using 6-cyclopropylmethoxy-5-methyl-pyridine-2-carboxylic acid (Example 36 d) and (S)-α-(2-methylpropyl)-2-thiazolemethanamine (Example 56 d) as starting materials, MS (EI): m/e=360.2 [M+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09321727B2 |
| Source dataset | uspto-grants-2016_04 |
| ORD ID | ord-163ac065354c4338aa84c649abd29985 |
| Source note | uspto-grants-2016_04 |