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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 632085Generated: October 26, 2026

2-(1,2,4-Oxadiazol-3-yl)propan-2-amine → 5-Cyclopropyl-6-cyclopropylmethoxy-pyridine-2-carboxylic acid (1-methyl-1-[1,2,4]oxadiazol-3-yl-ethyl)-amide

https://huagongshe.com/reaction/632085

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-(1,2,4-Oxadiazol-3-yl)propan-2-amineHCID 43559118—
Reactant5-Cyclopropyl-6-cyclopropylmethoxy-pyridine-2-carboxylic acidHCID 71087346—
Product5-Cyclopropyl-6-cyclopropylmethoxy-pyridine-2-carboxylic acid (1-methyl-1-[1,2,4]oxadiazol-3-yl-ethyl)-amideHCID 71105581—

Reaction Steps

The title compound was synthesized in analogy to Example 1, using 5-cyclopropyl-6-cyclopropylmethoxy-pyridine-2-carboxylic acid (Example 42 a) and 1-methyl-1-[1,2,4]oxadiazol-3-yl-ethylamine (CAN 1153757-41-5) as starting materials, MS (LC/MS): 343.1 (M+H).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09321727B2
Source datasetuspto-grants-2016_04
ORD IDord-427e5b7f623d4b0b8dabcecec05e2b62
Source noteuspto-grants-2016_04