Tert-Butylamine → HCID 71087307, compound

HRID 632448Notes

Reaction equation

HRID 632448 reaction equation
[CH:1]1([C:4]2[CH:5]=[CH:6][C:7]([C:17]([NH:19][C:20]([CH2:26]C)([CH2:24]C)[C:21](O)=O)=[O:18])=[N:8][C:9]=2[O:10][CH2:11][CH:12]2[CH2:16][CH2:15][CH2:14][O:13]2)[CH2:3][CH2:2]1.C(N)(C)(C)C>>[C:20]([NH:19][C:17]([C:7]1[CH:6]=[CH:5][C:4]([CH:1]2[CH2:3][CH2:2]2)=[C:9]([O:10][CH2:11][CH:12]2[CH2:16][CH2:15][CH2:14][O:13]2)[N:8]=1)=[O:18])([CH3:26])([CH3:21])[CH3:24]

Participants

3

Reactant 2

HCID 6385Tert-ButylamineHCID 710876312-(5-Cyclopropyl-6-((tetrahydrofuran-2-yl)methoxy)picolinamido)-2-ethylbutanoic acid

Product 1

HCID 71087307HCID 71087307, compound

Procedure

The title compound was synthesized in analogy to Example 1, using 2-(5-cyclopropyl-6-((tetrahydrofuran-2-yl)methoxy)picolinamido)-2-ethylbutanoic acid (Example 166 b) and tert-butylamine (CAN 75-64-9) as starting materials. MS (EI): m/e=319.4 [M+H]+.

Sources & evidence

ORD record
ord-6bba69a8ba9e441d963d8f496791808b
Source dataset
uspto-grants-2016_04
Patent number
US09321727B2

Reaction notes

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