HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Amino-4-methylpyridine → 5-Iodo-4-methylpyridin-2-amine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Amino-4-methylpyridine | HCID 1533 | — |
| Reactant | N-Iodosuccinimide | HCID 120273 | — |
| Product | 5-Iodo-4-methylpyridin-2-amine | HCID 17750195 | — |
Reaction Steps
The title compound is synthesized according to general procedure GP1 starting from 2.0 g (18 mmol) 4-methyl-pyridin-2-ylamine and 4.2 g (18 mmol) NIS. Yield after precipitation from the reaction mixture: 3.6 g (83%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09321771B2 |
| Source dataset | uspto-grants-2016_04 |
| ORD ID | ord-1c3b09e1bb1249c1a40a7f012db1d4db |
| Source note | uspto-grants-2016_04 |