huagongshe.com
HRID632895

反应详情

EQUATION

反应方程式

HRID 632895 的结构方程式

REACTANTS

反应物

2
结构：O=C([O-])[O-].[K+].[K+]
HCID11430

Potassium Carbonate

CK2O3

结构：Cc1nc(N)ccc1C#C[Si](C)(C)C
HCID59255232

未命名化合物

PRODUCTS

生成物

1
结构：C#Cc1ccc(N)nc1C
HCID55285938

5-Ethynyl-6-methylpyridin-2-amine

C8H8N2

AUXILIARIES

试剂、催化剂与溶剂

1
结构：CO
溶剂HCID887

Methanol

CH4O

PROCEDURE

实验过程

The title compound is synthesized according to general procedure GP3 starting from 4.3 g (21.0 mmol) 6-methyl-5-trimethylsilanylethynyl-pyridin-2-ylamine and 1.5 g (10.5 mmol) K2CO3 in 30 mL MeOH. The product is purified by chromatography on silica gel using a DCM/MeOH gradient. Yield: 3.6 g.

WORKUP

后处理

  1. customThe product is purified by chromatography on silica gel using a DCM/MeOH gradient