HuagongsheHuagongshe Chemistry Print Report · For research reference only
Isopropylamine → N1-(4-chloro-3-(pyridin-2-yl)phenyl)-N4-isopropylterephthalamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Isopropylamine | HCID 6363 | — |
| Reactant | 4-(4-Chloro-3-(pyridin-2-yl)phenylcarbamoyl)benzoic acid | HCID 66877887 | — |
| Product | N1-(4-chloro-3-(pyridin-2-yl)phenyl)-N4-isopropylterephthalamide | HCID 58614667 | — |
Reaction Steps
50 mg of 4-(4-chloro-3-(pyridin-2-yl)phenylcarbamoyl)benzoic acid was coupled to isopropylamine via Procedure G. The product was purified on reverse phase HPLC to yield N1-(4-chloro-3-(pyridin-2-yl)phenyl)-N4-isopropylterephthalamide. MS (Q1) 394 (M)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09321761B2 |
| Source dataset | uspto-grants-2016_04 |
| ORD ID | ord-8ac290f4df7648888783130130558d22 |
| Source note | uspto-grants-2016_04 |