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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 63340Generated: October 29, 2026

Acetonitrile → 3-(6-(Cycloheptyloxy)pyridin-2-yl)-3-oxopropanenitrile

https://huagongshe.com/reaction/63340

Reaction equation

Participants

RoleNameHCIDCharge
ReactantAcetonitrileHCID 6342—
ReactantHCID 86694648HCID 86694648—
Product3-(6-(Cycloheptyloxy)pyridin-2-yl)-3-oxopropanenitrileHCID 86694647—

Reaction Steps

CH3CN addition to methyl 6-(cycloheptyloxy)picolinate following the method described in Example 6 gave 3-(6-(cycloheptyloxy)pyridin-2-yl)-3-oxopropanenitrile as a yellow oil which was used in the next step without further purification. Yield (1.29 g, quant.).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09447078B2
Source datasetuspto-grants-2016_09
ORD IDord-3d6fee8f8d0d47a6a1166ee2fe3b8b62
Source noteuspto-grants-2016_09