HCID 86704546, compound → HCID 86704547, compound

HRID 633460Notes

Reaction equation

HRID 633460 reaction equation
[Si:1]([O:8][CH2:9][C:10]1([CH2:30][O:31][Si:32]([C:35]([CH3:38])([CH3:37])[CH3:36])([CH3:34])[CH3:33])[O:15][C:14]2[CH:16]=[CH:17][C:18]([N+:20]([O-:22])=[O:21])=[CH:19][C:13]=2[N:12]=[C:11]1[NH:23][NH:24][C:25](OCC)=[O:26])([C:4]([CH3:7])([CH3:6])[CH3:5])([CH3:3])[CH3:2]>CN(C=O)C>[Si:1]([O:8][CH2:9][C:10]1([CH2:30][O:31][Si:32]([C:35]([CH3:36])([CH3:38])[CH3:37])([CH3:33])[CH3:34])[O:15][C:14]2[CH:16]=[CH:17][C:18]([N+:20]([O-:22])=[O:21])=[CH:19][C:13]=2[N:12]2[C:25](=[O:26])[NH:24][N:23]=[C:11]12)([C:4]([CH3:6])([CH3:7])[CH3:5])([CH3:3])[CH3:2]

Participants

3

Reactant 1

HCID 86704546HCID 86704546, compound

Product 1

HCID 86704547HCID 86704547, compound

Reagents, catalysts & solvents 1

HCID 6228DimethylformamideSolvent

Procedure

Ethyl 2-(2,2-bis(((tert-butyldimethylsilyl)oxy)methyl)-6-nitro-2H-benzo[b][1,4]oxazin-3-yl)hydrazine-1-carboxylate (4 g) was dissolved in DMF (34 ml). The reaction mixture was microwaved at 200° C. for 10 min. The reaction solution was evaporated to give 4,4-bis(((tert-butyldimethylsilyl)oxy)methyl)-8-nitro-2,4-dihydro-1H-benzo[b][1,2,4]triazolo[4,3-d][1,4]oxazin-1-one.

Workup

  1. customThe reaction mixture was microwaved at 200° C. for 10 min
  2. customThe reaction solution was evaporated

Sources & evidence

ORD record
ord-42ce18b7556e4b2a94961d4bb04f2e9f
Source dataset
uspto-grants-2016_04
Patent number
US09321763B2

Reaction notes

Loading…