HuagongsheHuagongshe Chemistry Print Report · For research reference only
Trifluoroacetic acid → HCID 71203152, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Trifluoroacetic acid | HCID 6422 | — |
| Reactant | HCID 71186588 | HCID 71186588 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 71203152 | HCID 71203152 | — |
Reaction Steps
55 μl of trifluoroacetic acid were added to a solution of 39 mg of tert-butyl {-4-[5-(2,5-difluorophenoxy)-7-propyloxazolo[5,4-d]pyrimidin-2-yl]-2,6-dimethylphenoxy}acetate in 0.4 ml of dichloromethane, and the mixture was stirred at room temperature for 16 h. The reaction was then concentrated under reduced pressure, and the residue was triturated with diisopropyl ether, filtered off with suction and dried. This gave 21 mg (60%) of the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09321787B2 |
| Source dataset | uspto-grants-2016_04 |
| ORD ID | ord-3e39ee784a6e47efa14faa5f537aa9d6 |
| Source note | uspto-grants-2016_04 |