HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → 2-Amino-7-(2-cyano-benzyl)-1,7-dihydro-purin-6-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | 2-(Bromomethyl)benzonitrile | HCID 89599 | — |
| Reactant | Guanosine Hydrate | HCID 135705230 | — |
| Solvent | Dimethyl Sulfoxide | HCID 679 | — |
| Product | 2-Amino-7-(2-cyano-benzyl)-1,7-dihydro-purin-6-one | HCID 136065587 | — |
Reaction Steps
Prepared by reacting 20.00 g of guanosine-hydrate with 22.54 g of 2-cyano-benzylbromide in dimethylsulphoxide at 60° C. and subsequent treatment with 57 ml of conc. hydrochloric acid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09321791B2 |
| Source dataset | uspto-grants-2016_04 |
| ORD ID | ord-9626b5ed14ec474db812289f305bbb41 |
| Source note | uspto-grants-2016_04 |