Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Hydrazine | HCID 9321 | — |
| Reactant | HCID 90002242 | HCID 90002242 | — |
| Reactant | 2-(2-Methyl-6-(tetrahydrofuran-3-yl)phenoxy)acetohydrazide | HCID 90002699 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | HCID 90002256 | HCID 90002256 | 90% |
Reaction Steps
Synthesis of 2-(2-methyl-6-(tetrahydrofuran-3-yl)phenoxy)acetohydrazide: methyl 2-(2-methyl-6-(tetrahydrofuran-3-yl)phenoxy)acetate (141 mg, 0.56 mmol) and hydrazine (0.03 mL, 0.6 mmol) were dissolved in EtOH 2 mL, followed by stirring at 100° C. for 12 hours. After the completion of the reaction, the reaction mixture was concentrated under reduced pressure to obtain 2-(2-(furan-3-yl)-6-methylphenoxy)acetohydrazide (127 mg, 90%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US09447083B2 |
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| Source dataset | uspto-grants-2016_09 |
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| ORD ID | ord-1bbfb45c28f84f6cbc642f992f912dc3 |
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| Source note | uspto-grants-2016_09 |
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