HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrogen Bromide → 2-bromo-1-(6-methoxypyrid-3-yl)ethanone hydrobromide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrogen Bromide | HCID 260 | — |
| Reactant | Bromine | HCID 24408 | — |
| Reactant | 5-Acetyl-2-methoxypyridine | HCID 10534837 | — |
| Solvent | Acetic Acid | HCID 176 | — |
| Product | 2-bromo-1-(6-methoxypyrid-3-yl)ethanone hydrobromide | HCID 87943397 | — |
Reaction Steps
230 mg (1.52 mmol) of 1-(6-methoxypyrid-3-yl)ethanone, 413 μl (7.61 mmol) of hydrobromic acid, 87 μl (1.67 mmol) of bromine and 5 mL of glacial acetic acid were used in the reaction. After precipitation with ethyl ether and filtration, 430 mg of 2-bromo-1-(6-methoxypyrid-3-yl)ethanone hydrobromide are obtained, the characteristics of which are as follows:
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09321790B2 |
| Source dataset | uspto-grants-2016_04 |
| ORD ID | ord-2a65da26f5064c17b78872675916a922 |
| Source note | uspto-grants-2016_04 |