HuagongsheHuagongshe Chemistry Print Report · For research reference only
Potassium Carbonate → 3-(1-(6-Amino-9H-purin-9-yl)ethyl)-4-m-tolyl-1H-isochromen-1-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | 3-(1-Bromoethyl)-4-m-tolyl-1H-isochromen-1-one | HCID 118131032 | — |
| Reactant | HCID 178508693 | HCID 178508693 | — |
| Product | 3-(1-(6-Amino-9H-purin-9-yl)ethyl)-4-m-tolyl-1H-isochromen-1-one | HCID 118131234 | 54.7% |
Reaction Steps
The title compound was made in a similar way as that of the compound of example 1, using 3-(1-bromoethyl)-4-m-tolyl-1H-isochromen-1-one (intermediate C5, 80 mg, 0.23 mmol), 9H-purin-6-amine (63 mg, 0.46 mmol) and K2CO3 (64.4 mg, 0.46 mmol) to give the title compound (50 mg, 54%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09321776B2 |
| Source dataset | uspto-grants-2016_04 |
| ORD ID | ord-8c081339483641afb15dc5c187cd7a47 |
| Source note | uspto-grants-2016_04 |