Methyl chloroformate → HCID 21260326, compound

Participants

Reaction Steps

Methyl chloroformate (16.35 ml, 0.173 mol) was added to a solution of 2,4difluorophenol (25 g, 0.192 mol) and sodium hydroxide (8.1 g, 0.203 mol) in water (140 ml). The mixture was stirred at ambient temperature for 2 hours and then extracted with ethyl acetate. The extract was washed with water, dried (MgSO4) and the volatiles removed by evaporation to give 2,4-difluoro-1-methoxycarbonyloxybenzene (32 g, 89%).

Provenance & Evidence