Nitric Acid → HCID 21260309, compound

Participants

Reaction Steps

A mixture of concentrated nitric acid (4 ml) and concentrated sulphuric acid (4 ml) was added slowly to a cooled mixture of 2,4-difluoro-1-methoxycarbonyloxybenzene (50 g, 0.027 mol) in concentrated sulphuric acid (4 ml) such that the reaction temperature was maintained below 30° C. The mixture was stirred for a further 3 hours, diluted with ice/water and the precipitated product collected by filtration washed with water and dried to give 2,4-difluoro-5-methoxycarbonyloxy-1-nitrobenzene (2.8 g, 45%).

Provenance & Evidence