Glycidol → HCID 22965537, compound

HRID 635122Notes

Reaction equation

HRID 635122 reaction equation
O=[CH:2][C@@H:3]([C@H:5]([C@H:7]([C@@H:9]([CH2:11][OH:12])[OH:10])[OH:8])[OH:6])[OH:4].[NH2:13]C(O)(O)CC.[CH2:19]1[O:21][CH:20]1[CH2:22][OH:23]>>[OH:21][CH:20]([CH2:22][OH:23])[CH2:19][NH:13][CH2:2][C@@H:3]([C@H:5]([C@H:7]([C@@H:9]([CH2:11][OH:12])[OH:10])[OH:8])[OH:6])[OH:4]

Participants

4

Reactant 3

HCID 11164GlycidolHCID 3037556(2R,3S,4S,5R)-2,3,4,5,6-pentahydroxyhexanalHCID 19962668HCID 19962668, compound

Product 1

HCID 22965537HCID 22965537, compound

Procedure

Each diastereoisomer can also be obtained by coupling D-galactose with the pure enantiomer of the aminopropanediol or by the reaction of the enantiomers of glycidol on N-(2,3,4,5,6-pentahydroxyhexyl)benzylamide as follows:

Workup

  1. customEach diastereoisomer can also be obtained

Sources & evidence

ORD record
ord-2fd872b7c59140a6854e330f46fe583f
Source dataset
uspto-grants-2001_02
Patent number
US06187285B1

Reaction notes

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