反应详情

To a solution of 4-Iodo-aniline (15 g, 69 mmol) in dry CH2Cl2 (100 ml) was added acetic anhydride(14.09 g, 138 mmol) at room temperature, the reaction mixture was then stirred for 2 hr. The gray color precipitate formed during the reaction was filtered, washed with ether and collected, the mother solution was concentrated to dryness and AcOEt was added, the resulting precipitate was filtered, washed with ether and combined with the previous solid as the desired product (15.95 g, 88.7%).

1. customThe gray color precipitate
2. customformed during the reaction
3. filtrationwas filtered
4. washwashed with ether
5. customcollected
6. concentrationthe mother solution was concentrated to dryness and AcOEt
7. additionwas added
8. filtrationthe resulting precipitate was filtered
9. washwashed with ether