Pyrrolidine → HCID 23435906, compound

HRID 635235Notes

Reaction equation

[C:1]([O:5][C:6]([N:8]1[CH2:13][CH2:12][C:11](=[C:14]([Br:29])[C:15]2[CH:20]=[CH:19][C:18]([C:21]([N:23]3[CH2:28][CH2:27]O[CH2:25][CH2:24]3)=[O:22])=[CH:17][CH:16]=2)[CH2:10][CH2:9]1)=[O:7])([CH3:4])([CH3:3])[CH3:2].N1CCCC1>>[C:1]([O:5][C:6]([N:8]1[CH2:9][CH2:10][C:11](=[C:14]([Br:29])[C:15]2[CH:16]=[CH:17][C:18]([C:21]([N:23]3[CH2:28][CH2:27][CH2:25][CH2:24]3)=[O:22])=[CH:19][CH:20]=2)[CH2:12][CH2:13]1)=[O:7])([CH3:4])([CH3:3])[CH3:2]

Participants

Reactant 2

HCID 31268Pyrrolidine

HCID 23435899HCID 23435899, compound

Product 1

HCID 23435906HCID 23435906, compound

Procedure

Same procedure as described for the preparation of compound 82, but using pyrrolidine in place of morpholine.

Sources & evidence

ORD record: ord-897f643e70a04312b5b433772a8b2dea
Source dataset: uspto-grants-2001_02
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06187792B1

Reaction notes

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