Hydrochloric Acid → HCID 178478642, compound

Participants

Reaction Steps

In the same manner as in Example 102 except that 3-(2,4,5,6-tetrahydrocyclopentapyrazol-3-yl)propionic acid obtained in Starting Material Synthesis Example 4 and 1-(4-fluorophenyl)piperazine were used instead of 3-(4,5,6,7-tetrahydro-2H-indazol-3-yl)propionic acid obtained in Starting Material Synthesis Example 1 and 4-(4-chlorophenyl)piperidine and then by a conventional treatment using hydrochloric acid, 3-(3-(4-(4-fluorophenyl)piperazin-1-yl)propyl)-2,4,5,6-tetrahydrocyclopentapyrazole dihydrochloride dihydrate was obtained, m.p. 228-230° C.

Provenance & Evidence