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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 635312Generated: October 30, 2026

1-(4-Chlorophenyl)piperazine → 4-(4-Chlorophenyl)piperidine

https://huagongshe.com/reaction/635312

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-(4-Chlorophenyl)piperazineHCID 97478—
Reactant3-(4,5,6,7-tetrahydro-2H-indazol-3-yl)propanoic acidHCID 178525369—
Product4-(4-Chlorophenyl)piperidineHCID 1203613—

Reaction Steps

In the same manner as in Example 102 except that 3-(5-benzoyl-4,5,6,7-tetrahydro-2H-pyrazolo[4,3-c]pyridin-3-yl)propionic acid obtained in Starting Material Synthesis Example 8 and 1-(4-chlorophenyl)piperazine were used instead of 3-(4,5,6,7-tetrahydro-2H-indazol-3-yl)propionic acid obtained in Stating Material Synthesis Example 1 and 4-(4-chlorophenyl)piperidine, 5-benzyl-3-(3-(4-(4chlorophenyl)piperazin-1-yl)propyl)-4,5,6,7-tetrahydro-2H-pyrazolo[4,3-c]pyridine was obtained.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06187774B1
Source datasetuspto-grants-2001_02
ORD IDord-ffea1de8435646fcbc941d4eb0a7722f
Source noteuspto-grants-2001_02