HCID 178505853, compound → HCID 178505854, compound

Participants

Reaction Steps

5-Benzyl-3-(3-(4-(4-fluorophenyl)piperazin-1-yl)propyl)-4,5,6,7-tetrahydro-2H-pyrazolo[4,3-c]pyridine (0.5 g) obtained in Example 139 was dissolved in ethanol (10 ml), and Raney nickel (0.2 g) was added to perform catalytic reduction. After the completion of the reaction, the reaction mixture was filtered through celite and the filtrate was concentrated under reduced pressure. The obtained residue was subjected to silica gel column chromatography to give 3-(3-(4-(4-fluorophenyl)piperazin-1-yl)propyl)-4,5,6,7-tetrahydro-2H-pyrazolo[4,3-c]pyridine,

Provenance & Evidence