1-Phenylpiperazine → HCID 178420458, compound

HRID 635328Notes

Reaction equation

HRID 635328 reaction equation
[C:1]1([N:7]2[CH2:12][CH2:11][NH:10][CH2:9][CH2:8]2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[N:13]1[NH:14][C:15]([CH2:22][CH2:23][C:24](O)=O)=[C:16]2[C:21]=1[CH2:20][CH2:19][CH2:18]C2.ClC1C=CC(C2CCNCC2)=CC=1>>[C:1]1([N:7]2[CH2:12][CH2:11][N:10]([CH2:24][CH2:23][CH2:22][C:15]3[NH:14][N:13]=[C:21]4[CH2:20][CH2:19][CH2:18][C:16]=34)[CH2:9][CH2:8]2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1

Participants

4

Reactant 3

HCID 70961-PhenylpiperazineHCID 12036134-(4-Chlorophenyl)piperidineHCID 1785253693-(4,5,6,7-tetrahydro-2H-indazol-3-yl)propanoic acid

Product 1

HCID 178420458HCID 178420458, compound

Procedure

In the same manner as in Example 102 except that 3-(2,4,5,6-tetrahydrocyclopentapyrazol-3-yl)propionic acid obtained in Starting Material Synthesis Example 4 and 1-phenylpiperazine are used instead of 3-(4,5,6,7-tetrahydro-2H-indazol-3-yl)propionic acid obtained in Starting Material Synthesis Example 1 and 4-(4-chlorophenyl)piperidine, 2,4,5,6-tetrahydro-3-(3-(4-phenylpiperazin-1-yl)propyl)cyclopentapyrazole is obtained.

Workup

  1. customobtained

Sources & evidence

ORD record
ord-d20949d7b3e54d81a2d5c0779cae31c6
Source dataset
uspto-grants-2001_02
Patent number
US06187774B1

Reaction notes

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