1-(2-Pyridyl)piperazine → HCID 178420460, compound

HRID 635335Notes

Reaction equation

HRID 635335 reaction equation
[N:1]1[CH:6]=[CH:5][CH:4]=[CH:3][C:2]=1[N:7]1[CH2:12][CH2:11][NH:10][CH2:9][CH2:8]1.[N:13]1[NH:14][C:15]([CH2:22][CH2:23][C:24](O)=O)=[C:16]2[C:21]=1[CH2:20][CH2:19][CH2:18][CH2:17]2.Cl[C:28]1C=CC(C2CCNCC2)=CC=1>>[N:1]1[CH:6]=[CH:5][CH:4]=[CH:3][C:2]=1[N:7]1[CH2:8][CH2:9][N:10]([CH2:28][CH2:24][CH2:23][CH2:22][C:15]2[NH:14][N:13]=[C:21]3[C:16]=2[CH2:17][CH2:18][CH2:19][CH2:20]3)[CH2:11][CH2:12]1

Participants

4

Reactant 3

HCID 944591-(2-Pyridyl)piperazineHCID 12036134-(4-Chlorophenyl)piperidineHCID 1785253693-(4,5,6,7-tetrahydro-2H-indazol-3-yl)propanoic acid

Product 1

HCID 178420460HCID 178420460, compound

Procedure

In the same manner as in Example 102 except that 4-(4,5,6,7-tetrahydro-2H-indazol-3-yl)-n-butyric acid obtained in Starting Material Synthesis Example 3 and 1-(2-pyridyl)piperazine were used instead of 3-(4,5,6,7-tetrahydro-2H-indazol-3-yl)propionic acid obtained in Starting Material Synthesis Example 1 and 4-(4chlorophenyl)piperidine, 3-(4-(4-(2-pyridyl)piperazin-1-yl)butyl)-4,5,6,7-tetrahydro-2H-indazole was obtained.

Workup

  1. customobtained

Sources & evidence

ORD record
ord-7809d7bd7c4f45559fb78ccd8efd7990
Source dataset
uspto-grants-2001_02
Patent number
US06187774B1

Reaction notes

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