1-(2-Methoxy-5-nitrophenyl)ethanone → 1-(5-Amino-2-methoxyphenyl)ethanone

HRID 635423Notes

Reaction equation

HRID 635423 reaction equation
[CH3:1][O:2][C:3]1[CH:8]=[CH:7][C:6]([N+:9]([O-])=O)=[CH:5][C:4]=1[C:12](=[O:14])[CH3:13]>CO.C(Cl)(Cl)Cl>[NH2:9][C:6]1[CH:7]=[CH:8][C:3]([O:2][CH3:1])=[C:4]([C:12](=[O:14])[CH3:13])[CH:5]=1

Participants

3

Reactant 1

HCID 186151041-(2-Methoxy-5-nitrophenyl)ethanone

Product 1

HCID 155794431-(5-Amino-2-methoxyphenyl)ethanone

Reagents, catalysts & solvents 1

HCID 21584188Chloroform methanolSolvent

Procedure

The above-identified compound (2.13 g) was obtained by processing Intermediate 72 (2.50 g) through reaction and after-treatment in accordance with the procedures of the step C of Example 63. Rf=0.38 (methanol/chloroform of 1/19).

Workup

  1. customthrough reaction

Sources & evidence

ORD record
ord-d1d4db27cd774808a4fd133d5ce6000b
Source dataset
uspto-grants-2001_02
Patent number
US06187809B1

Reaction notes

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