HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methanol → Methyl 2-amino-4-(4-octylphenyl)butyrate hydrochloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methanol | HCID 887 | — |
| Reactant | 2-Amino-4-(4-octylphenyl)butanoic acid hydrochloride | HCID 70148713 | — |
| Solvent | Thionyl Chloride | HCID 24386 | — |
| Product | Methyl 2-amino-4-(4-octylphenyl)butyrate hydrochloride | HCID 22618877 | — |
Reaction Steps
To a solution of 2-Amino-4-(4-octylphenyl)butanoic acid hydrochloride (20 g) in methanol (500 ml), thionyl chloride (7.2 ml) was added under ice-cooling and the mixture was left standing overnight. The reaction mixture was concentrated under reduced pressure to give the subject compound (16 g). MS: 305(M+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06187821B1 |
| Source dataset | uspto-grants-2001_02 |
| ORD ID | ord-453bd35cef7044e6bbc7ded006f87dbd |
| Source note | uspto-grants-2001_02 |