Furfural → HCID 70059216, compound

HRID 635880Notes

Reaction equation

HRID 635880 reaction equation
O1C=CC([C:6]2([C:19](=[O:21])[CH3:20])[N:13]3[C:9]([S:10][C:11]4[CH2:18][CH2:17][CH2:16][CH2:15][CH2:14][C:12]=43)=[N:8][CH2:7]2)=C1.[O:22]1[CH:26]=[CH:25][CH:24]=[C:23]1[CH:27]=O>>[O:22]1[CH:26]=[CH:25][CH:24]=[C:23]1[CH:27]=[CH:20][C:19]([C:6]1[N:13]2[C:9]([S:10][C:11]3[CH2:18][CH2:17][CH2:16][CH2:15][CH2:14][C:12]=32)=[N:8][CH:7]=1)=[O:21]

Participants

3

Reactant 2

HCID 7362FurfuralHCID 70057946HCID 70057946, compound

Product 1

HCID 70059216HCID 70059216, compound

Procedure

3-(3-Furanyl)-1-(6,7,8,9-tetrahydro-5H-cyclohept[d]imidazo[2,1-b]thiazol-3-yl)-ethanone (Formula P-1), 3.51 g, was condensed with 2-Furaldehyde (1.99 g) by non-critical variations of PREPARATION 15 to give 3-(2-Furanyl)-1-(6,7,8,9-tetrahydro-5H-cyclohept[d]imidazo[2,1-b]thiazol-3-yl)-2-propene-1-one (Formula P-2, X=0), m.p. 161-162°.

Workup

  1. customby non-critical variations of PREPARATION 15

Sources & evidence

ORD record
ord-b8dc4cf487d14099aaac04c7fc3bcb12
Source dataset
uspto-grants-2001_02
Patent number
US06191124B1

Reaction notes

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