Aluminium lithium hydride → HCID 467125, compound

HRID 635881Notes

Reaction equation

HRID 635881 reaction equation
[O:1]1[CH:5]=[CH:4][CH:3]=[C:2]1[CH:6]=[CH:7][C:8]([C:10]1[N:17]2[C:13]([S:14][C:15]3[CH2:22][CH2:21][CH2:20][CH2:19][CH2:18][C:16]=32)=[N:12][CH:11]=1)=[O:9].[H-].[H-].[H-].[H-].[Li+].[Al+3]>>[O:1]1[CH:5]=[CH:4][CH:3]=[C:2]1[CH2:6][CH2:7][CH:8]([C:10]1[N:17]2[C:13]([S:14][C:15]3[CH2:22][CH2:21][CH2:20][CH2:19][CH2:18][C:16]=32)=[N:12][CH:11]=1)[OH:9]

Participants

3

Reactant 2

HCID 21226445Aluminium lithium hydrideHCID 70059216HCID 70059216, compound

Product 1

HCID 467125HCID 467125, compound

Procedure

3-(2-Furanyl)-1-(6,7,8,9-tetrahydro-5H-cyclohept[d]imidazo[2,1-b]thiazol-3-yl)-propene-1-one (Formula P-2, X=0), 0.94 g, was reduced with LiAlH4 by non-critical variations of EXAMPLE 23 to provide α-[2-(2-Furanyl)ethyl]-6,7,8,9-tetrahydro-5H-cyclohept[d]imidazo[2,1-b]thiazol-3-methanol (Formula P-5, X=0), after two crystallizations from ethanol.

Sources & evidence

ORD record
ord-c20d78d857c14a609bc8cb45bf87b396
Source dataset
uspto-grants-2001_02
Patent number
US06191124B1

Reaction notes

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