反应详情

11 mmol of N-bromosuccinimide and 0.22 g of azobisisobutyronitrile (Aldrich) are added to a solution of 10 mmol of 6-cyano-2,2-dimethyl-chroman in 30 ml of carbon tetrachloride and the suspension thus obtained is heated to boiling under a reflux condenser for 3 hours. Insoluble succinimide is then filtered off, the solvent is distilled off and the residue is crystallized under a mixture of n-hexane and diisopropyl ether.

1. customthe suspension thus obtained
2. temperatureis heated
3. filtrationInsoluble succinimide is then filtered off
4. distillationthe solvent is distilled off
5. customthe residue is crystallized under a mixture of n-hexane and diisopropyl ether