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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 63599Generated: October 29, 2026

Sodium Hydroxide → 3-phenyl-5-(2-methoxyphenyl)-1H-pyrrolo[2,3-b]pyridine

https://huagongshe.com/reaction/63599

Reaction equation

Participants

RoleNameHCIDCharge
ReactantSodium HydroxideHCID 14798—
ReactantHCID 90239025HCID 90239025—
SolventMethanolHCID 887—
Product3-phenyl-5-(2-methoxyphenyl)-1H-pyrrolo[2,3-b]pyridineHCID 72792688—

Reaction Conditions

Temperature80 °C

Reaction Steps

To a solution of 3-phenyl-5-(2-methoxyphenyl)-1-(phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridine (374 mg, 0.85 mmol) in methanol (2.3 ml) is added NaOH (260 μl of 2 N solution in water, 0.51 mmol). The mixture is heated at 80° C. for 1 hour and then cooled at room temperature.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09447093B2
Source datasetuspto-grants-2016_09
ORD IDord-f7d8d3f9edf343c89ac88e5f318006dd
Source noteuspto-grants-2016_09