HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 63599Generated: October 29, 2026
Sodium Hydroxide → 3-phenyl-5-(2-methoxyphenyl)-1H-pyrrolo[2,3-b]pyridine
https://huagongshe.com/reaction/63599
Participants
| Role | Name | HCID | Charge |
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| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | HCID 90239025 | HCID 90239025 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | 3-phenyl-5-(2-methoxyphenyl)-1H-pyrrolo[2,3-b]pyridine | HCID 72792688 | — |
Reaction Steps
To a solution of 3-phenyl-5-(2-methoxyphenyl)-1-(phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridine (374 mg, 0.85 mmol) in methanol (2.3 ml) is added NaOH (260 μl of 2 N solution in water, 0.51 mmol). The mixture is heated at 80° C. for 1 hour and then cooled at room temperature.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US09447093B2 |
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| Source dataset | uspto-grants-2016_09 |
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| ORD ID | ord-f7d8d3f9edf343c89ac88e5f318006dd |
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| Source note | uspto-grants-2016_09 |
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