Indene → Lithium, 1H-inden-1-yl-

HRID 636029Notes

Reaction equation

HRID 636029 reaction equation
[CH2:1]1[C:9]2[C:4](=[CH:5][CH:6]=[CH:7][CH:8]=2)[CH:3]=[CH:2]1.[Li:10]CCCC>CCCCCC>[CH-:1]1[C:9]2[C:4](=[CH:5][CH:6]=[CH:7][CH:8]=2)[CH:3]=[CH:2]1.[Li+:10]

Participants

4

Reactant 2

HCID 7219IndeneHCID 178418339Butyllithium

Product 1

HCID 11116044Lithium, 1H-inden-1-yl-Yield 89.1%

Reagents, catalysts & solvents 1

HCID 8058HexaneSolvent

Procedure

Indene (10.0 g, 0.0861 moles) was stirred in hexane (150 mL) as n-BuLi (0.8783 moles, 54.8 mL of 1.6 M solution in hexane) was added drop wise. The mixture was allowed to stir overnight at room temperature during which time a solid precipitated. After the reaction period the solid was collected via suction filtration, washed with hexane, dried under vacuum, and was used without further purification or analysis (9.35 g, 89.1% yield).

Workup

  1. additionwas added drop wise
  2. customprecipitated
  3. customAfter the reaction period the solid
  4. filtrationwas collected via suction filtration
  5. washwashed with hexane
  6. customdried under vacuum
  7. customwas used without further purification or analysis (9.35 g, 89.1% yield)

Sources & evidence

ORD record
ord-9d8c74b2498a4f4b86e5d237bedfb5e3
Source dataset
uspto-grants-2001_02
Patent number
US06191245B1

Reaction notes

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