Isopropanol → HCID 67639350, compound

HRID 636033Notes

Reaction equation

HRID 636033 reaction equation
[C:1]([O:4][CH2:5][C:6]([CH3:10])([CH2:8][OH:9])[CH3:7])(=[O:3])[OH:2].ClCCl.C(O)(C)C.[C:18]1(=[O:25])[O:24][CH2:23][CH2:22][CH2:21][CH2:20][CH2:19]1>CO>[C:1]([O:4][CH2:5][C:6]([CH3:10])([CH2:8][OH:9])[CH3:7])(=[O:2])[OH:3].[C:18]1(=[O:25])[O:24][CH2:23][CH2:22][CH2:21][CH2:20][CH2:19]1

Participants

6

Reactant 4

HCID 3776IsopropanolHCID 6344Dichloromethane2×HCID 10401epsilon-CAPROLACTONEHCID 21943848HCID 21943848, compound

Product 1

HCID 67639350HCID 67639350, compound

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

6.59 g, (550 mmol) of neopentyl glycol carbonate were measured and introduced into the same apparatus as in Example I-1 under nitrogen atmosphere. 3 ml of dry dichloromethane were introduced through a syringe apparatus, under nitrogen flow. 0.077 ml, (1 mmol) of isopropyl alcohol was then added and then 1 ml of the 0.3mmol/ml dichloromethane solution of 2,6-ditert-butyl-4-methylphenol-bis-substituted titanium-type Lewis acid (A) was then added and the mixture was reacted at 60° C. for 4.0 hours under stirring. It was verified that the monomer had been consumed, and an extremely small amount of sample was taken out. Then, 5.7 g, (50 mmol) of ε-caprolactone was then added and the polymerisation was continued under stirring for 1.5 hour at room temperature. The reacting compound was poured into 300mi of methanol and the white precipitate was dried under reduced pressure. 11.0 g of block copolymer were thus obtained.

Workup

  1. customthe mixture was reacted at 60° C. for 4.0 hours
  2. customhad been consumed
  3. stirringunder stirring for 1.5 hour at room temperature
  4. customthe white precipitate was dried under reduced pressure
  5. custom11.0 g of block copolymer were thus obtained

Sources & evidence

ORD record
ord-6b22ff409afc436ea79cfbfc7245b262
Source dataset
uspto-grants-2001_02
Patent number
US06191250B1

Reaction notes

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