3,5-Dimethoxyaniline → HCID 85782707, compound

HRID 636075Notes

Reaction equation

HRID 636075 reaction equation
[CH3:1][O:2][C:3]1[CH:4]=[C:5]([CH:7]=[C:8]([O:10][CH3:11])[CH:9]=1)[NH2:6]>C1(C)C(C)=CC=CC=1>[CH3:11][O:10][C:8]1[CH:7]=[C:5]([NH:6][C:8](=[O:10])[CH2:9][C:3](=[O:2])[CH2:4][CH2:5][CH3:7])[CH:4]=[C:3]([O:2][CH3:1])[CH:9]=1

Participants

3

Reactant 1

HCID 663013,5-Dimethoxyaniline

Product 1

HCID 85782707HCID 85782707, compoundYield 153.2%

Reagents, catalysts & solvents 1

HCID 7237O-XyleneSolvent

Procedure

3,5-Dimethoxy aniline 1(14.5 g, 92.5 mmol) in xylene (50 mL) was treated with 2,2-dimethyl-6-propyl-4H-1,3-dioxinone (17.3 g, 101.7 mmol) worked up and purified as described for 9 to afford e N-(3, 5-dimethoxyphenyl)-3-oxo-hexanamide (10, 18.8 g) in 77% yield as an oily liquid.

Workup

  1. custompurified

Sources & evidence

ORD record
ord-aea317d3151d4bc4a3cb923bd6f66467
Source dataset
uspto-grants-2001_02
Patent number
US06191279B1

Reaction notes

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