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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 636115Generated: October 30, 2026

2-Thiopheneacetic acid → 2-[(2-Thienyl)acetamido]butyric acid isobutyl ester

https://huagongshe.com/reaction/636115

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Thiopheneacetic acidHCID 15970—
ReactantIsobutyl 2-aminobutyrateHCID 13743360—
Product2-[(2-Thienyl)acetamido]butyric acid isobutyl esterHCID 54443682—

Reaction Steps

Following General Procedure I′ above and using 2-thiopheneacetic acid (Aldrich) and iso-butyl 2-aminobutyrate (prepared following General Procedure J′ above), the title compound was prepared. The reaction was monitored by tlc on silica gel and purification was by filtration as described in the general procedure.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06191166B1
Source datasetuspto-grants-2001_02
ORD IDord-cc33725ff17f48298c517e0447818dd2
Source noteuspto-grants-2001_02